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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
30
Human Site:
S650
Identified Species:
41.25
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S650
K
G
R
P
R
K
D
S
R
L
M
P
V
S
L
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S650
K
G
R
P
R
K
D
S
R
L
M
P
V
S
L
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S771
K
G
R
P
R
K
D
S
R
L
M
P
V
S
L
Dog
Lupus familis
XP_543550
1017
111618
S650
K
G
R
P
R
K
D
S
R
L
M
P
V
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S648
K
G
R
P
R
K
D
S
R
L
L
P
M
S
L
Rat
Rattus norvegicus
NP_001129232
1015
111665
S648
K
G
R
P
R
K
D
S
R
L
L
P
V
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S656
K
G
R
P
R
K
D
S
R
L
V
P
V
T
L
Frog
Xenopus laevis
Q8QFR2
1013
112021
Q646
G
R
P
R
K
E
S
Q
R
L
M
S
V
S
L
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
A643
K
G
R
P
R
K
D
A
K
M
M
M
P
I
S
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
P658
M
A
A
S
I
A
Q
P
L
T
Q
T
T
S
P
Fruit Fly
Dros. melanogaster
O17468
1047
113397
D668
C
G
L
L
R
I
W
D
I
A
K
K
V
V
S
Honey Bee
Apis mellifera
XP_001122939
838
91355
H489
P
N
V
T
S
S
V
H
S
T
N
I
N
S
Q
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
V586
L
K
T
Q
E
G
T
V
L
M
E
A
P
E
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
V615
V
C
L
E
A
R
P
V
E
R
G
A
G
D
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
T671
D
G
S
L
Q
V
Y
T
K
C
G
R
R
A
M
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
S491
N
K
A
V
T
L
K
S
G
K
K
R
V
A
P
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
E649
E
R
G
V
L
Q
E
E
T
S
L
E
D
A
T
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
N.A.
86.6
40
53.3
6.6
20
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
53.3
73.3
6.6
20
6.6
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
13.3
N.A.
40
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
12
0
6
6
0
6
0
6
0
12
0
18
0
% A
% Cys:
6
6
0
0
0
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
0
48
6
0
0
0
0
6
6
0
% D
% Glu:
6
0
0
6
6
6
6
6
6
0
6
6
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
59
6
0
0
6
0
0
6
0
12
0
6
0
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
6
6
0
0
6
0
0
6
0
6
0
% I
% Lys:
48
12
0
0
6
48
6
0
12
6
12
6
0
0
0
% K
% Leu:
6
0
12
12
6
6
0
0
12
48
18
0
0
0
48
% L
% Met:
6
0
0
0
0
0
0
0
0
12
36
6
6
0
12
% M
% Asn:
6
6
0
0
0
0
0
0
0
0
6
0
6
0
0
% N
% Pro:
6
0
6
48
0
0
6
6
0
0
0
42
12
0
12
% P
% Gln:
0
0
0
6
6
6
6
6
0
0
6
0
0
0
12
% Q
% Arg:
0
12
48
6
53
6
0
0
48
6
0
12
6
0
0
% R
% Ser:
0
0
6
6
6
6
6
48
6
6
0
6
0
53
12
% S
% Thr:
0
0
6
6
6
0
6
6
6
12
0
6
6
6
6
% T
% Val:
6
0
6
12
0
6
6
12
0
0
6
0
53
6
0
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _